No way, this is not what tmux is for, sorry.

There are situations where you need, for example, to send a file to, let's say, network device (router, switch, ...).

Zmodem is thirty years old. Last time I used it was perhaps twenty years ago. If you really have devices which only support zmodem for transferring files you can do it without magic support by tmux. Strong thumbs down from me. Practically any other change to tmux would have greater value.

It may be useful if you are several ssh hops away. Like "Me" → Machine1 →Machine2. Other option is to set up several ssh tunnels prelimitary.

When has anything been dismissed in Linux just because it's old? Linux itself is that old...

Anyhow, there are many environments where you have to pass through one or more jump boxes. If I have to retrieve a file or more, that's more than a few bytes, kicking off zmodem removes the pain of scp the file between each level, or setting up complex port forwards (which are often disabled by policy).

Practically not adding this valuable feature means users are forced into an outdated usage pattern.

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