I found a solution for the problem.

OpenSSL 1.1.1b need the command -writerand instead of -rand for the random number generation if no .rnd file is present. I changed this in the following files:

node-opcua-pki/dist/lib/pki/certificate_authority.js
node-opcua-pki/dist/lib/pki/toolbox.js
node-opcua-pki/lib/pki/certificate_authority.ts
node-opcua-pki/lib/pki/toolbox.ts

Now the certificates can be created.

I found a solution for the problem.

OpenSSL 1.1.1b need the command -writerand instead of -rand for the random number generation if no .rnd file is present. I changed this in the following files:

node-opcua-pki/dist/lib/pki/certificate_authority.js
node-opcua-pki/dist/lib/pki/toolbox.js
node-opcua-pki/lib/pki/certificate_authority.ts
node-opcua-pki/lib/pki/toolbox.ts

Now the certificates can be created.

Hi @Kiesel38.
how do you make it writable ?
openssl rand <the listed file you mention ?>

Can somebody give me the full command pls?
i was using this command (by finding the exact command from some 2 year old video): sudo openssl req -x509 -nodes -days 365 -newkey rsa:2048 -keyout /etc/ssl/private/nginx.key -out /etc/ssl/certs/nginx.crt

And I'm getting this error: "Can't load /root/.rnd into RNG
140121868997056:error:2406F079:random number generator:RAND_load_file:Cannot open file:../crypto/rand/randfile.c:88:Filename=/root/.rnd"

I'm using latest openssh (just downloaded) on Ubuntu 18.04.x (upgraded)

@bathindahelper You can manually create the file with openssl rand -out <randFile> -hex 256. In your case sudo openssl rand -out /root/.rnd -hex 256.

@Ejdamm : Hej.. I am dealing with a relevant problem when i give this command:
openssl req -x509 -nodes -days 365 -newkey rsa:1024 -keyout mycert.pem -out mycert.pem

the terminal returns back the following:

Can't load /home/ubuntu/.rnd into RNG
140115398300096:error:2406F079:random number generator:RAND_load_file:Cannot open file:../crypto/rand/randfile.c:88:Filename=/home/ubuntu/.rnd

@ppapias1987

Have you tried creating the file that is missing, eg /home/ubuntu/.rnd?
openssl rand -out /home/ubuntu/.rnd -hex 256
Also, your key and cert is named the same. Switch to -keyout mykey.pem

I had the same problem, and then created the .rnd myself as you said. I'm trying to create a self-signed certificate, and this time, when I ran openssl req -x509 -newkey rsa:2048 -keyout ca_key.pem -out ca_cert.pem -days 365 I no longer got an error, but it hangs on "Generating a RSA private key". This is a bit of a different problem, but I was wondering if you could help me out?
This StackExchange answer said it lacks entropy.
Would that mean I need a bigger .rnd file? I'm terribly confused, and new to this stuff.

@Ejdamm

Yes! I tried it before without success, however i managed to figure it out later. Sorry for the delay to respond.

I had the same problem, and then created the .rnd myself as you said. I'm trying to create a self-signed certificate, and this time, when I ran openssl req -x509 -newkey rsa:2048 -keyout ca_key.pem -out ca_cert.pem -days 365 I no longer got an error, but it hangs on "Generating a RSA private key". This is a bit of a different problem, but I was wondering if you could help me out?
This StackExchange answer said it lacks entropy.
Would that mean I need a bigger .rnd file? I'm terribly confused, and new to this stuff.

If you are working on windows, you should set environment variable to path of .rnd file, i.e.
set RANDFILE=.rnd

@bathindahelper You can manually create the file with openssl rand -out <randFile> -hex 256. In your case sudo openssl rand -out /root/.rnd -hex 256.

Thanks....
This solution was helpful to solve the problem.
I wanted to create self signed certificate using following command:
openssl req -key private.pem -new -x509 -days 365 -subj "/C=IR/" -out SelfSigned.crt